PKPDsim: Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD) models described by differential equation (DE) systems. Simulation using ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015) <doi:10.1016/j.vascn.2015.03.004>).

Version: 1.1.1
Depends: R (≥ 3.0.2)
Imports: Rcpp (≥ 0.12.9), BH, data.table, stringr, MASS, randtoolbox, jsonlite, stats, parallel, magrittr
LinkingTo: BH, Rcpp (≥ 0.12.9)
Suggests: httr, testthat (≥ 3.0.0), mockery
Published: 2022-04-01
Author: Ron Keizer [aut, cre], Jasmine Hughes [aut], Dominic Tong [aut], Kara Woo [aut], InsightRX [cph, fnd]
Maintainer: Ron Keizer <ron at>
License: MIT + file LICENSE
NeedsCompilation: yes
Materials: README NEWS
In views: MixedModels
CRAN checks: PKPDsim results


Reference manual: PKPDsim.pdf


Package source: PKPDsim_1.1.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): PKPDsim_1.1.1.tgz, r-oldrel (arm64): PKPDsim_1.1.1.tgz, r-release (x86_64): PKPDsim_1.1.1.tgz, r-oldrel (x86_64): PKPDsim_1.1.1.tgz
Old sources: PKPDsim archive


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