bayesCT: Simulation and Analysis of Adaptive Bayesian Clinical Trials

Simulation and analysis of Bayesian adaptive clinical trials for binomial, Gaussian, and time-to-event data types, incorporates historical data and allows early stopping for futility or early success. The package uses novel and efficient Monte Carlo methods for estimating Bayesian posterior probabilities, evaluation of loss to follow up, and imputation of incomplete data. The package has the functionality for dynamically incorporating historical data into the analysis via the power prior or non-informative priors.

Version: 0.99.3
Depends: R (≥ 2.10)
Imports: bayesDP, dplyr, purrr, survival, magrittr (≥ 1.5)
Suggests: testthat, rmarkdown, pkgdown, devtools, knitr
Published: 2020-07-01
DOI: 10.32614/CRAN.package.bayesCT
Author: Thevaa Chandereng ORCID iD [aut, cre, cph], Donald Musgrove [aut, cph], Tarek Haddad [aut, cph], Graeme Hickey [aut, cph], Timothy Hanson [aut, cph], Theodore Lystig [aut, cph]
Maintainer: Thevaa Chandereng <chandereng at>
License: GPL-3
NeedsCompilation: no
Materials: README
In views: Bayesian, MissingData
CRAN checks: bayesCT results


Reference manual: bayesCT.pdf
Vignettes: bayesian trial


Package source: bayesCT_0.99.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): bayesCT_0.99.3.tgz, r-oldrel (arm64): bayesCT_0.99.3.tgz, r-release (x86_64): bayesCT_0.99.3.tgz, r-oldrel (x86_64): bayesCT_0.99.3.tgz
Old sources: bayesCT archive


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